Mouse Anti-Human Complement C5a/C5a des Arg Monoclonal Antibody (CTJS-723)(Cat#: CTA-528)

This product is an anti-Human Complement C5a/C5a des Arg Monoclonal antibody (CTJS-723) generated from the Mouse. The antibody can be used for WB; ELISA; IHC; Funcs.

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Specifications
Clonality Monoclonal
Clone CTJS-723
Host Animal Mouse
Isotype IgG2a
Immunogen Recombinant C5a. The exact sequence is proprietary.
Species Reactivity Human
Applications WB; ELISA; IHC; Funcs
Application Notes WB: 1:50
IHC: 1:50
ELISA: 1:50
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human complement C5a/C5a des Arg.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 100 µg
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Type Primary Antibody
Target
Target Name C5a
Alternative Names Complement C5a; C5a des-Arg; Inactivated C5a
Gene ID 727
UniProt ID P01031
Information
Introduction Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. Once complement C5a is produced, it rapidly metabolised inti C5a desArg by a serum enzyme carboxypeptidase B through removal of the C terminal arginine. Compared with C5a, C5a des-Arg is a much less potent anaphylatoxin that alsi induces C5a biological activities.


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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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