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Dengue Virus Envelope Virus-like Particles (DENV Envelope VLPs) (CAT#: S01YF-0922-KX1547)

Datasheet
Recombinant Dengue Virus-like Particle (DENV VLPs) are produced in mammalian HEK293 human cells, assembled with Envelope proteins. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. DENV VLPs can be used in the development of DENV diagnostics and in vaccine development and R&D (including use as an immunogen).

Product Specifications

  • Structural Proteins
  • Envelope protein
  • Expression Systems
  • HEK293 expression system
  • Form
  • Liquid
  • Alternative Names
  • Dengue Virus-like Particle; DENV VLPs; VLPs; Virus-like Particles; DENV; Dengue Virus
  • Storage
  • Store at -80 °C long term. Avoid repeated freeze/thaw cycles.
  • Sequence
  • mrcigisnrdfvegvsggswvdivlehgscvttmaknkptldfelikteakhpatlrkycieakltntttasrcptqgepslneeqdkrfvckhsmvdrgwgngcglfgkggivtcamftckknmegkivqpenleytivitphsgeenavgndtgkhgkeikvtpqssiteaeltgygtvtmecsprtgldfnemvllqmenkawlvhrqwfldlplpwlpgadtqgsnwiqketlvtfknphakkqdvvvlgsqegamhtaltgateiqmssgnllftghlkcrlrmdklqlkgmsysmctgkfkvvkeiaetqhgtivirvqyegdgspckipfeimdlekrhvlgrlitvnpivtekdspvnieaeppfgdsyiiigvepgqlklswfkkgssigqmfettmrgakrmailgdtawdfgslggvftsigkalhqvfgaiygaafsgvswtmkiligvvitwigmnsrstslsvslv-HHHHHH

Virus Background

  • Virus Family
  • Flaviviridae
  • Virus Species
  • Dengue virus
  • Virus Overview
  • The DENV genome is about 11000 bases of positive-sense, single stranded RNA (ssRNA) that codes for three structural proteins (capsid protein C, membrane protein M, envelope protein E) and seven nonstructural proteins (NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5). It also includes short noncoding regions on both the 5' and 3' ends. Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease.
  • Virus Structure
  • Enveloped, positive-sense, single-stranded RNA virus
  • Related Disease
  • Dengue disease

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