Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCreative Biolabs offers unique and adaptable droplet microfluidic antibody discovery technology for single antigen-special antibody secreting B-cell (ASC) screening to retrieve high-quality native mAbs with picodroplets (pL to nL). Due to physical containment and flexibility, microfluidics technology is adopted by our Native™ Antibody Discovery platform to enable faster, less costly and more effective ASCs screening for antibody discovery at the speed of millions of cells a day.
Droplet Microfluidic Technology
The novel technology makes it possible to screen tens of millions of cells with pL to nL volume aqueous droplets (picodroplets) in oil at a rate of over 100,000 per minute. By separating cells into individual picodroplets for single antigen-specific cell isolation, the systems ensure that you get a more accurate measurement of antibody secretion. In fact, the microfluidic platform can produce, manipulate, analyze, sort, fuse, split, retrieve, and dispense millions of picodroplets per biochip, which has compelling advantages for rare cell applications as well as low volumes regarding cell sample, reagents. We can apply any known virtual bioassay for measuring the functional activity of each secreted antibody.
Fig.1 Principle of Microfluidics Technology.
Creative Biolabs brings expertise and knowledge to every link of Native™ Antibody Discovery process, including immunization→cell enrichment→screening→recovery→next-generation sequencing→bioinformatics. The unique droplet microfluidic technology speeds up the process at the step of isolating activated single antibody-secreting cells in picoliter-volume chambers from various tissues including blood, bone marrow and B cell plasma, which allows secreted antibodies to be detected within hours with a variety of bead-based and cell-based assay formats. Based on binding properties and antibody function, small volume chambers mean that millions of cells can be screened. Combing with the deep technical expertise and state-of-the-art automation during cell processing and recovery, we can quickly and effectively identify rare antibodies with the desired properties.
Key Benefits of Microfluidic System
These unique features enable the fully integrated platform to become a novel and powerful solution to find antibody against complex targets. Creative Biolabs can also screen diverse targets, including soluble and complex membrane proteins from multiple species to meet your current and future needs flexibly. Combining high-throughput screening with enhanced sensitivity and flexibility, the microfluidic platform can deliver high-quality mAb therapeutic candidates with exceptional speed.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
