Stability Evaluation Service for Exosome Product

Overview Services Features FAQs

Overview

Large-scale production of exosomes can meet the needs of academia and industry for exosome products, laying a solid foundation for transforming exosome research into applications. In the large-scale production process, the stability evaluation of exosome products is indispensable. In order to meet the needs of customers, Creative Biolabs has specially deployed the stability evaluation business of exosome products.

Why Need to Evaluate the Stability of Exosome Products?

There are differences in the stability of exosomes under different preparation methods and storage conditions. Improper handling may damage and even degrade exosomes, resulting in changes in their composition, activity, and function, thereby affecting their application effects. Therefore, the evaluation of exosome product stability helps in the following ways.

  • Screening out the most suitable exosome products for subsequent research or clinical trials.
  • Determining factors such as optimal storage temperature, storage time, and storage buffer composition for exosome products
  • Providing an important basis for the production process optimization and quality control standards for exosome products
  • Ensuring the stability and application effect of exosome products.

Services

Stability Evaluation Service of Exosome Products at Creative Biolabs

Using rich experience and advanced technology platforms, Creative Biolabs will provide the best exosome product stability evaluation service.

STABILITY EVALUATION ANGLE EVALUATION REASON TEST METHODS EVALUATION METHOD
Preparation method Although some preparation methods ensure the purity of exosomes, they have a certain degree of damage to exosomes. Currently, commonly used exosome isolation methods include ultracentrifugation, ultrafiltration, affinity chromatography, size-exclusion chromatography, and Precipitation. The quality of exosomes obtained by these methods is also different. Quality comparison of exosomes from different preparation methods
Storage temperature Since frequent freezing/thawing processes may cause damage to exosomes during cryopreservation, it is necessary to evaluate the stability of exosomes after 1-2 freezing/thawing cycles. Freeze/thaw test
In general, exosome products can be cryogenic or freezing. Therefore, it is necessary to evaluate the stability of cryogenic or frozen exosomes. Storage temperature comparison
Storage time As biologically active vesicles, exosomes may be degraded and lose their effectiveness after being placed for a long time. Therefore, it is necessary to compare the differences in parameters between fresh exosomes and exosome products after a period of storage. Comparison at different storage time points
Stock buffer composition Adding some protective agents to the storage buffer can improve the stability of exosomes. Therefore, it is necessary to compare the protective effects of different buffer formulations on exosomes. Stock buffer composition comparison
Other feasible evaluation angles Concrete analysis of specific situations

Exosome analysis by NTA, TEM and nano flow cytometry. (Creative Biolabs Original)Fig.1 Exosome evaluation by nanoparticle size analysis, transmission electron microscopy and CD81 identification.

Features

  • Multidimensional stability testing
  • Professional data analysis and reporting
  • Expert improvement recommendations
  • Other related one-stop services

Through these refined analyses and evaluations, we will ensure that the quality and stability of exosome products are maximized, and help customers ensure the reliability of exosome products. If you need to evaluate the stability of your exosome product, please contact us and tell us the specific information about the product and testing requirements to get a complete quotation.

FAQs

Q: How do storage temperature and duration affect the stability of exosomes?

A: Storage temperature and duration are critical factors affecting the stability of exosomes. We conduct systematic tests to determine the optimal storage conditions, ensuring that exosomes maintain their activity and efficacy during storage and transport.

Q: What information do clients need to provide for stability assessment?

A: Clients need to provide detailed information about the source of the exosomes, their intended application, and the preparation method. This information helps us to develop a targeted stability assessment plan.

Q: How are the assessment results communicated to the client?

A: We provide detailed data analysis and reports, including all results from the stability tests. Additionally, we offer expert improvement recommendations based on the assessment results to help clients optimize the stability of their exosome products.

For Research Use Only. Cannot be used by patients.
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