Exosome Profiling Services

Overview Services Equipment Applications FAQs

Overview

Exosomes are specifically secreted vesicles from living cells, responsible for intercellular communication and playing a critical role in immune systems. Since exosomes composed of numerous RNA, proteins, lipids, cytokines, several large-scale analysis such as proteomics and transcriptomics can often be performed. These vesicles also show potential for cancer diagnostics and determination of other diseases because they transport molecular contents of cells from which they originate. Though the detection and molecular analysis of exosomes is technically challenging, Creative Biolabs has a highly experienced team equipped with advanced platforms to achieve a variety of exosome profiling regarding its contents.

Exosome Profiling Services in Creative Biolabs

The study and analysis for exosomes is an emerging approach among worldwide researchers from every walk of biomedical fields. In order to obtain expert data interpretation and technical support, Creative Biolabs offers a variety of exosomal profiling platforms for the isolation, purification, quantification, and analysis of required exosomes.

Equipment

Flow cytometry (FC) – The magnetic beads can capture the immunomagnetic beads of exosomes, which exhibits clear and definite FFC/SSC testing with 1 hour.
Electron microscopy (EM) – You can directly perform a scanning electron microscope (SEM) analysis to observe the pure and specialized exosomes using our magnetic separation technology.
Optical microscopy (OM) – Exosome RNA or membrane components can be labeled, allowing exosomes to be visible under the optical microscope.

Applications

Aided by Creative Biolabs, exosomes are able to transfer information in the form of abundant functions, and these biological processes in research fields are listed as below.

Cell signaling
Immune system
Exchange of pathogenic organisms
Stem cell function

Cell adhesion and motility
Inflammation
Tumor progression
Diseases (e.g. Alzheimer's and Parkinson's)

When customers access exosome profiling services at Creative Biolabs, not only do they get high-quality exosome production or detailed data delivery, but also get in-depth scientific support from experts with years of exosome experience. Besides, we can also offer other reagents and tools for in vitro and in vivo tracing to help the further understanding of exosomes. If there is no related service about exosomes you need, please don’t hesitate to contact us for your specific requirements.

Reference

Isola, A. L.; Chen, S. Exosomes: the messengers of health and disease. Curr Neuropharmacol. 2017, 15(1): 157-165.

FAQs

What is exosome analysis, and why is it important in drug development research?

Exosome analysis involves studying the composition, function, and characteristics of exosomes, small vesicles secreted by cells. Understanding exosomes is crucial in drug development as they play key roles in intercellular communication, disease progression, and drug delivery mechanisms.

How can exosome analysis services benefit our drug development projects?

Exosome analysis services offer valuable insights into disease mechanisms, biomarker discovery, and drug efficacy assessment. By understanding exosome profiles in various biological samples, researchers can identify potential therapeutic targets, develop novel diagnostic tools, and optimize drug delivery strategies.

What types of samples can be analyzed using our exosome analysis services?

Our exosome analysis services support a wide range of sample types, including cell culture supernatants, blood plasma, serum, urine, and cerebrospinal fluid. We tailor our analysis protocols to accommodate diverse sample matrices and research objectives, ensuring accurate and reliable results.

How does our company ensure the accuracy and reliability of exosome analysis results?

We adhere to rigorous quality control measures throughout the exosome analysis process, from sample handling and processing to data interpretation. Our team of experienced scientists utilizes validated protocols and state-of-the-art instrumentation to ensure the accuracy and reproducibility of our results.

What level of expertise and support can you expect when using our exosome analysis services?

Our team consists of exosome biology experts with extensive experience in conducting exosome analysis for drug development research. We provide personalized support and guidance at every step of the project, from experimental design and sample preparation to data analysis and interpretation.