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Magic™ Antibody Discovery - Human E-Selectin / CD62E (22-556) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1396F)

Datasheet
This membrane protein is Human E-Selectin / CD62E (22-556). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • E-Selectin / CD62E
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 84.8 kDa. The protein migrates as 96-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Trp 22 - Phe 556 (Accession # NP_000441.2).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • E-Selectin / CD62E
  • Full Name
  • selectin E
  • Introduction
  • The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
  • Alternative Names
  • ELAM; ESEL; CD62E; ELAM1; LECAM2; E-selectin; CD62 antigen-like family member E; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2

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