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Magic™ Antibody Discovery - Human IL-31 RA (20-519) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0238F)

Datasheet
This membrane protein is Human IL-31 RA (20-519). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-31 RA
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 83.5 kDa. The protein migrates as 105-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 20 - Glu 519 (Accession # Q8NI17-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-31 RA
  • Full Name
  • interleukin 31 receptor A
  • Introduction
  • The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
  • Alternative Names
  • CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; zcytoR17; interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; class I cytokine receptor; cytokine receptor-like 3; gp130-like monocyte receptor; soluble type I cytokine receptor CRL3

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