Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
With over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
This membrane protein is Human Netrin receptor DCC / DCC (32-1097). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.
Product Specifications
Host Species
Human
Target Protein
Netrin receptor DCC / DCC
Protein Length
ECD
Molecular Weight
The protein has a calculated MW of 119.5 kDa
Sequence
AA Phe 32 - Asn 1097 (Accession # P43146-1).
Product Description
Application
SDS-PAGE
Expression Systems
HEK293
Tag
His tag at the C-terminus
Protein Format
Soluble
Reconstitution
Please see Certificate of Analysis for specific instructions.
Buffer
Please contact us for detailed information.
Contact us for customized product form or formulation.
Target
Target Protein
Netrin receptor DCC / DCC
Full Name
DCC netrin 1 receptor
Introduction
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
Alternative Names
CRC18; CRCR1; MRMV1; HGPPS2; IGDCC1; NTN1R1; netrin receptor DCC; colorectal cancer suppressor; deleted in colorectal carcinoma; immunoglobulin superfamily DCC subclass member 1; putative colorectal tumor suppressor; tumor suppressor protein DCC