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Magic™ Membrane Protein Human ACVRL1 (Activin A receptor like type 1) Full Length (CAT#: MPC1934K) Made to Order

Datasheet
This product is a 56.1 kDa Human ACVRL1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACVRL1
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 56.1 kDa
  • TMD
  • 1
  • Sequence
  • MTLGSPRKGLLMLLMALVTQGDPVKPSRGPLVTCTCESPHCKGPTCRGAW
    CTVVLVREEGRHPQEHRGCGNLHRELCRGRPTEFVNHYCCDSHLCNHNVS
    LVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRRRQEKQ
    RGLHSELGESSLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVAR
    QVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVL
    LRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLAL
    RLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADLG
    LAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWA
    FGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPT
    IPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNSPEKPK
    VIQ

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ACVRL1
  • Full Name
  • Activin A receptor like type 1
  • Introduction
  • This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
  • Alternative Names
  • ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; serine/threonine-protein kinase receptor R3; TGF-B superfamily receptor type I; activin A receptor type II-like 1; activin A receptor type IL; activin A receptor, type II-like kinase 1; Activin A receptor like type 1
  • Gene ID
  • 94

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