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Magic™ Membrane Protein Human ADAM28 (ADAM metallopeptidase domain 28) Expressed in CHO for Antibody Discovery, Partial (72-623aa) (CAT#: MPX0802K)

Datasheet
This product is a 62 kDa Human ADAM28 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADAM28
  • Protein Length
  • Partial (72-623aa)
  • Protein Class
  • Protease
  • Molecular Weight
  • 62 kDa
  • TMD
  • 1
  • Sequence
  • LKKNKNLLAPGYTETYYNSTGKEITTSPQ
    IMDDCYYQGHILNEKVSDASISTCRGLRGYFSQGDQRYFIEPLSPIHRDG
    QEHALFKYNPDEKNYDSTCGMDGVLWAHDLQQNIALPATKLVKLKDRKVQ
    EHEKYIEYYLVLDNGEFKRYNENQDEIRKRVFEMANYVNMLYKKLNTHVA
    LVGMEIWTDKDKIKITPNASFTLENFSKWRGSVLSRRKRHDIAQLITATE
    LAGTTVGLAFMSTMCSPYSVGVVQDHSDNLLRVAGTMAHEMGHNFGMFHD
    DYSCKCPSTICVMDKALSFYIPTDFSSCSRLSYDKFFEDKLSNCLFNAPL
    PTDIISTPICGNQLVEMGEDCDCGTSEECTNICCDAKTCKIKATFQCALG
    ECCEKCQFKKAGMVCRPAKDECDLPEMCNGKSGNCPDDRFQVNGFPCHHG
    KGHCLMGTCPTLQEQCTELWGPGTEVADKSCYNRNEGGSKYGYCRRVDDT
    LIPCKANDTMCGKLFCQGGSDNLPWKGRIVTFLTCKTFDPEDTSQEIGMV
    ANGTKCGDNKVCINAECVDIEKA

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in water.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >70%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in MES and NaCl.

Target

  • Target Protein
  • ADAM28
  • Full Name
  • ADAM metallopeptidase domain 28
  • Introduction
  • This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ADAM28; MDCL; MDC-L; eMDCII; ADAM 28; eMDC II; disintegrin and metalloproteinase domain-containing protein 28; epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymis secretory sperm binding protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; ADAM metallopeptidase domain 28

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