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Magic™ Membrane Protein Human TLR1 (Toll like receptor 1) Expressed in NS0 for Antibody Discovery, Partial (22-578aa) (CAT#: MPX0208K)

Datasheet
This product is a 89.9 kDa Human TLR1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TLR1
  • Protein Length
  • Partial (22-578aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 89.9 kDa
  • TMD
  • 1
  • Sequence
  • SEESEFLVDRSKNGLIHVPKDLSQKTTIL
    NISQNYISELWTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDL
    SHNKLVKISCHPTVNLKHLDLSFNAFDALPICKEFGNMSQLKFLGLSTTH
    LEKSSVLPIAHLNISKVLLVLGETYGEKEDPEGLQDFNTESLHIVFPTNK
    EFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKLQTNPKLSNLT
    LNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK
    ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPF
    LHLDFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSL
    QQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDTIFRCLPPRIKVL
    DLHSNKIKSIPKQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHN
    SVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNIDQVSSEVLEGW
    PDSYKCDYPESYRGTLLKDFHMSELSCN

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • TLR1
  • Full Name
  • Toll like receptor 1
  • Introduction
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
  • Alternative Names
  • TLR1; TIL; CD281; rsc786; TIL. LPRS5; toll-like receptor 1; toll/interleukin-1 receptor-like protein; Toll like receptor 1

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