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Magic™ Membrane Protein Human ADGRB2 (Adhesion G protein-coupled receptor B2) Expressed in HEK293 for Antibody Discovery, Partial (21-911aa) (CAT#: MPX0018K)

This product is a 123 kDa Human ADGRB2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRB2
  • Protein Length
  • Partial (21-911aa)
  • Protein Class
  • GPCR
  • Molecular Weight
  • 123 kDa
  • TMD
  • 7
  • Sequence
  • LSVILSLRLATAFDPAPSACSALASGVLYG
    AFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPL
    DHYLVNFTCLRPSPEEAVAQAESEVGRPEEEEAEAAAGLELCSGSGPFTF
    LHFDKNFVQLCLSAEPSEAPRLLAPAALAFRFVEVLLINNNNSSQFTCGV
    LCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPGPPAAHTLSNA
    LVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEP
    GLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLR
    ETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKA
    CEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAG
    PAWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFR
    MCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAG
    EIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLR
    EHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTF
    KRATYVPSADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVED
    FIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKD
    WVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGHSH
    QRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPT
    QPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQ
    AAHTRCQCQHL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 250 μg/mL in PBS.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Target

  • Target Protein
  • ADGRB2
  • Full Name
  • Adhesion G protein-coupled receptor B2
  • Introduction
  • This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • BAI2; brain-specific angiogenesis inhibitor 2; ADGRB2; Adhesion G protein-coupled receptor B2

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