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Magic™ Membrane Protein Human APH1B (Aph-1 homolog B, gamma-secretase subunit) Full Length (CAT#: MPC1593K) Made to Order

This product is a 28.4 kDa Human APH1B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • APH1B
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 28.4 kDa
  • TMD
  • 7
  • Sequence
  • MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISS
    LVWFMARVIIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEG
    LKSINPGETAPSMRLLAYVSGLGFGIMSGVFSFVNTLSDSLGPGTVGIHG
    DSPQFFLYSAFMTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVS
    AQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLCQDKNFL
    LYNQRSR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • APH1B
  • Full Name
  • Aph-1 homolog B, gamma-secretase subunit
  • Introduction
  • This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
  • Alternative Names
  • APH1B; PSFL; APH-1B; PRO1328; TAAV688; gamma-secretase subunit APH-1B; APH1B gamma secretase subunit; anterior pharynx defective 1 homolog B; aph-1beta; Aph-1 homolog B, gamma-secretase subunit

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