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Magic™ Membrane Protein Human ASIC4 (Acid sensing ion channel subunit 4) Full Length (CAT#: MPC0404K) Made to Order

Datasheet
This product is a 70.1 kDa Human ASIC4 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ASIC4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 70.1 kDa
  • TMD
  • 2
  • Sequence
  • MLSGAAGAARRGGAALAPSLTRSLAGTHAGADSCAGADKGSHKETIEERD
    KRQQRQQRQRQHQGCGAAGSGSDSPTSGPHPVPVLFPLALSLEEQPLPPL
    PLGRAPGLLAREGQGREALASPSSRGQMPIEIVCKIKFAEEDAKPKEKEA
    GDEQSLLGAVAPGAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALA
    LLTSLAAFLYQAAGLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRF
    RHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQL
    ADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPRSSLPSRAGGMGSG
    LEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSP
    GFQTFVSCQEQRLTYLPQPWGNCRAESELREPELQGYSAYSVSACRLRCE
    KEAVLQRCHCRMVHMPDSLGGGPEGPCFCPTPCNLTRYGKEISMVRIPNR
    GSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGD
    LGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGIS
    TLGLQELKEQSPCPSRGRVEGGGVSSLLPNHHHPHGPPGGLFEDFAC

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ASIC4
  • Full Name
  • Acid sensing ion channel subunit 4
  • Introduction
  • This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
  • Alternative Names
  • ACCN4; BNAC4; acid-sensing ion channel 4; acid sensing ion channel family member 4; acid-sensing (proton-gated) ion channel family member 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; brain sodium channel 4; ASIC4; Acid sensing ion channel subunit 4

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