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Magic™ Membrane Protein Human CDH4 (Cadherin 4) Full Length (CAT#: MPC2047K) Made to Order

This product is a 100.2 kDa Human CDH4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDH4
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 100.2 kDa
  • TMD
  • 1
  • Sequence
  • MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILE
    GEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAF
    TVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKD
    TLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDND
    IPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAV
    DMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVT
    ANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDRE
    KVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE
    VPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTN
    EGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMD
    INEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDP
    ASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT
    LQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFE
    LPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPL
    SNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVL
    LFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQL
    QQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGL
    RAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWG
    PRFKKLADMYGGGEED

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CDH4
  • Full Name
  • Cadherin 4
  • Introduction
  • This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CDH4; CAD4; RCAD; R-CAD; cadherin-4; R-cadherin; cadherin 4, type 1, R-cadherin (retinal); cadherin 4, type 1, preproprotein; retinal cadherin; Cadherin 4

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