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Magic™ Membrane Protein Human CDS1 (CDP-diacylglycerol synthase 1) Full Length (CAT#: MPC4766K) Made to Order

Datasheet
This product is a made-to-order Human CDS1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDS1
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 6
  • Sequence
  • MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDL
    DSRTDSDIPEIPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLF
    FLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFL
    LCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVL
    SLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVI
    CNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSK
    YQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLY
    PFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRF
    DCQYLMATFVHVYITSFIRGPNPSKVLQQLLVLQPEQQLNIYKTLKTHLI

    EKGILQPTLKV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CDS1
  • Full Name
  • CDP-diacylglycerol synthase 1
  • Introduction
  • Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.
  • Alternative Names
  • CDS1; CDS 1; phosphatidate cytidylyltransferase 1; CDP-DAG synthase 1; CDP-DG synthase 1; CDP-DG synthetase 1; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; CDP-diglyceride pyrophosphorylase 1; CDP-diglyceride synthase 1; CDP-diglyceride synthetase 1; CTP:phosphatidate cytidylyltransferase 1; CDP-diacylglycerol synthase 1

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