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Magic™ Membrane Protein Human CHRND (Cholinergic receptor nicotinic delta subunit) Full Length (CAT#: MPC0473K) Made to Order

Datasheet
This product is a 58.8 kDa Human CHRND membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CHRND
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 58.8 kDa
  • TMD
  • 4
  • Sequence
  • MEGPVLTLGLLAALAVCGSWGLNEEERLIRHLFQEKGYNKELRPVAHKEE
    SVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISV
    LRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSS
    CPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIII
    DPEGFTENGEWEIVHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYI
    INILVPCVLISFMVNLVFYLPADSGEKTSVAISVLLAQSVFLLLISKRLP
    ATSMAIPLIGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHVLSEGVKKL
    FLETLPELLHMSRPAEDGPSPGALVRRSSSLGYISKAEEYFLLKSRSDLM
    FEKQSERHGLARRLTTARRPPASSEQAQQELFNELKPAVDGANFIVNHMR
    DQNNYNEEKDSWNRVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPPQ
    PFPGDPYSYNVQDKRFI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CHRND
  • Full Name
  • Cholinergic receptor nicotinic delta subunit
  • Introduction
  • The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • ACHRD; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS; acetylcholine receptor subunit delta; acetylcholine receptor, nicotinic, delta (muscle); cholinergic receptor, nicotinic delta; cholinergic receptor, nicotinic, delta (muscle); cholinergic receptor, nicotinic, delta polypeptide; CHRND; Cholinergic receptor nicotinic delta subunit

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