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Magic™ Membrane Protein Human CLCNKB (Chloride voltage-gated channel Kb) Full Length (CAT#: MPC0488K) Made to Order

This product is a 75.4 kDa Human CLCNKB membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLCNKB
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 75.4 kDa
  • TMD
  • 14
  • Sequence
  • MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDW
    YFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYP
    VALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVG
    LSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEM
    LVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMF
    RLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL
    FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLAS
    RLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFG
    TLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPE
    GIVAGGITNPIMPGGYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALP
    VLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHF
    MNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV
    QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFEL
    LNLHSLFVTSRGRAVGCVSWVEMKKAISNLTNPPAPK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CLCNKB
  • Full Name
  • Chloride voltage-gated channel Kb
  • Introduction
  • The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CLCKB; ClC-K2; ClC-Kb; chloride channel protein ClC-Kb; chloride channel, kidney, B; chloride channel, voltage-sensitive Kb; CLCNKB; Chloride voltage-gated channel Kb

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