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Magic™ Membrane Protein Human MICU1 (Mitochondrial calcium uptake 1) Full Length (CAT#: MPC2537K) Made to Order

This product is a made-to-order Human MICU1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MICU1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 1
  • Sequence
  • MFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGL
    LWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEKKTADLAPHPEEKK
    KKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPE
    DFVRSITPNEKQPEHLGLDQYIIKRFDGKKISQEREKFADEGSIFYTLGE
    CGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSII
    RSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQ
    RKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLK
    KHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVA
    RTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKD
    MGFTRLMQAMWKCAQETAWDFALPKQ

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII or Flag tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • MICU1
  • Full Name
  • Mitochondrial calcium uptake 1
  • Introduction
  • This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Alternative Names
  • MICU1; CALC; EFHA3; MPXPS; CBARA1; ara CALC; calcium uptake protein 1, mitochondrial; atopy-related autoantigen CALC; calcium-binding atopy-related autoantigen 1; Mitochondrial calcium uptake 1

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