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Magic™ Membrane Protein Human ERLIN2 (ER lipid raft associated 2) Full Length (CAT#: MPC1104K) Made to Order

Datasheet
This product is a 37.8 kDa Human ERLIN2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ERLIN2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 37.8 kDa
  • TMD
  • 1
  • Sequence
  • MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFH
    LMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAV
    YDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKL
    ALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQ
    KVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAF
    LAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKD
    IPNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ERLIN2
  • Full Name
  • ER lipid raft associated 2
  • Introduction
  • This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • ERLIN2; NET32; SPFH2; SPG18; C8orf2; Erlin-2; erlin-2; SPFH domain family, member 2; endoplasmic reticulum lipid raft-associated protein 2; epididymis secretory sperm binding protein; spastic paraplegia 18 (autosomal dominant); stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; UNQ2441/PRO5003/PRO9924; ER lipid raft associated 2

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