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Magic™ Membrane Protein Human GABRB3 (Gamma-aminobutyric acid type A receptor subunit beta3) Full Length (CAT#: MPC0517K) Made to Order

This product is a 54.1 kDa Human GABRB3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GABRB3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 54.1 kDa
  • TMD
  • 4
  • Sequence
  • MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDI
    RLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS
    GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVL
    YGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAV
    TGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQT
    YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
    PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAK
    NDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGI
    QYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDR
    WSRIVFPFTFSLFNLVYWLYYVN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII tag at N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GABRB3
  • Full Name
  • Gamma-aminobutyric acid type A receptor subunit beta3
  • Introduction
  • This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
  • Alternative Names
  • ECA5; DEE43; EIEE43; gamma-aminobutyric acid receptor subunit beta-3; GABA-alpha receptor beta-2 subunit; GABAA receptor beta-3 subunit; gamma-aminobutyric acid (GABA) A receptor, beta 3; gamma-aminobutyric acid A receptor beta 3; gamma-aminobutyric acid type A receptor beta3 subunit; GABRB3; Gamma-aminobutyric acid type A receptor subunit beta3

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