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Magic™ Membrane Protein Human EI24 (EI24 autophagy associated transmembrane protein) Full Length (CAT#: MPC2712K) Made to Order

This product is a made-to-order Human EI24 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EI24
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 5
  • Sequence
  • MADSVKTFLQDLARGIKDSIWGICTISKLDARIQQKREEQRRRRASSVLA
    QRRAQSIERKQESEPRIVSRIFQCCAWNGGVFWFSLLLFYRVFIPVLQSV
    TARIIGDPSLHGDVWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIA
    DLAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVG
    QLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLA
    FLTAMQSSYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFL
    SNRLFHKTVYLQSALSSSTSAEKFPSPHPSPAKLKATAGH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • EI24
  • Full Name
  • EI24 autophagy associated transmembrane protein
  • Introduction
  • This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8.
  • Alternative Names
  • EI24; EPG4; PIG8; TP53I8; etoposide-induced protein 2.4 homolog; ectopic P-granules autophagy protein 4 homolog; etoposide induced 2.4; p53-induced gene 8 protein; tumor protein p53 inducible protein 8; EI24 autophagy associated transmembrane protein

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