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Magic™ Membrane Protein Human GCNT2 (Glucosaminyl (N-acetyl) transferase 2 (I blood group)) Full Length (CAT#: MPC3621K) Made to Order

Datasheet
This product is a made-to-order Human GCNT2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GCNT2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 1
  • Sequence
  • MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACH
    QIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYT
    VTIHKDFGTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNA
    FLASKKESVVYGGISRLQADLNCLEDLVASEVPWKYVINTCGQDFPLKTN
    REIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHKNSYVIKTTKL
    KTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF
    WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYG
    NGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSW
    YF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • GCNT2
  • Full Name
  • Glucosaminyl (N-acetyl) transferase 2 (I blood group)
  • Introduction
  • This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Alternative Names
  • GCNT2; II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRCT13; bA421M1.1; bA360O19.2; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; I beta-1,6-N-acetylglucosaminyltransferase; Ii blood group; beta-1,6-N-acetylglucosaminyltransferase 2; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); Glucosaminyl (N-acetyl) transferase 2 (I blood group)

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