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Magic™ Membrane Protein Human GPR143 (G protein-coupled receptor 143) Full Length (CAT#: MPC0123K) Made to Order

This product is a 43.8 kDa Human GPR143 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR143
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 43.8 kDa
  • TMD
  • 7
  • Sequence
  • MASPRLGTFCCPTRDAATQLVLSFQPRAFHALCLGSGGLRLALGLLQLLP
    GRRPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVD
    SVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVDAYLVIRRSAG
    LSTILLYHIMAWGLATLLCVEGAAMLYYPSVSRCERGLDHAIPHYVTMYL
    PLLLVLVANPILFQKTVTAVASLLKGRQGIYTENERRMGAVIKIRFFKIM
    LVLIICWLSNIINESLLFYLEMQTDINGGSLKPVRTAAKTTWFIMGILNP
    AQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGAHPSPLMPHEN
    PASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPT
    HGDL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GPR143
  • Full Name
  • G protein-coupled receptor 143
  • Introduction
  • This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.
  • Alternative Names
  • OA1; NYS6; G-protein coupled receptor 143; ocular albinism 1; ocular albinism type 1 protein; GPR143; G protein-coupled receptor 143

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