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Magic™ Membrane Protein Human HIGD2A (HIG1 hypoxia inducible domain family member 2A) for Antibody Discovery (CAT#: MP0547J)

This product is a 11.3 kDa Human HIGD2A membrane protein expressed in HEK293T. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HIGD2A
  • Protein Length
  • Full-length
  • Protein Class
  • Transmembrane
  • Molecular Weight
  • 11.3 kDa
  • TMD
  • 2
  • Sequence
  • MATPGPVIPEVPFEPSKPPVIEGLSPTVYRNPESFKEKFVRKTRENPVVPIGCLATAAALTYGLYSFHRG
    NSQRSQLMMRTRIAAQGFTVAAILLGLAVTAMKSRP

Product Description

  • Expression Systems
  • HEK293T
  • Tag
  • C-Myc/DDK
  • Purification
  • Anti-DDK affinity column followed by conventional chromatography steps
  • Purity
  • > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Buffer
  • 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Target

  • Target Protein
  • HIGD2A
  • Full Name
  • HIG1 hypoxia inducible domain family member 2A
  • Introduction
  • The protein encoded by this gene is a subunit of the cytochrome c oxidase complex (complex IV), which is the terminal enzyme in the mitochondrial respiratory chain. The encoded protein is an inner mitochondrial membrane protein and is a functional ortholog of the yeast respiratory supercomplex factor 1 (Rcf1). In mouse, the orthologous protein enhances cell survival under conditions of hypoxia.
  • Alternative Names
  • RCF1b

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