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Magic™ Membrane Protein Human HTR1F (5-hydroxytryptamine receptor 1F) for Antibody Discovery (CAT#: MP1359J)

This product is a 60.2 kDa Human HTR1F membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR1F
  • Protein Length
  • Full-length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 60.2 kDa
  • TMD
  • 7
  • Sequence
  • MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • N-10xHis-SUMO
  • Reconstitution
  • Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).
  • Purity
  • >85% as determined by SDS-PAGE
  • Buffer
  • Liquid: Tris/PBS-based buffer, 5%-50% glycerol
    Lyophilized powder: Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • HTR1F
  • Full Name
  • 5-hydroxytryptamine receptor 1F
  • Introduction
  • G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
  • Alternative Names
  • 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F; HTR1F; HTR1EL5-hydroxytryptamine receptor 1F; 5-HT-1F; Serotonin receptor 1F

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