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Magic™ Membrane Protein Human KCNAB1 (Potassium voltage-gated channel subfamily A regulatory beta subunit 1) Full Length (CAT#: MPC1040K) Made to Order

Datasheet
This product is a 46.5 kDa Human KCNAB1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNAB1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 46.5 kDa
  • Sequence
  • MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPS
    GESQLRARQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLR
    VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVI
    LGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQ
    LEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA
    YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLAC
    GIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAER
    LGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVV
    NEIDNILRNKPYSKKDYRS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNAB1
  • Full Name
  • Potassium voltage-gated channel subfamily A regulatory beta subunit 1
  • Introduction
  • Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.
  • Alternative Names
  • KCNAB1; hKvb3; AKR6A3; KCNA1B; Kvb1.3; hKvBeta3; KV-BETA-1; voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; K+ channel Beta1a chain; potassium channel beta 3 chain; potassium channel beta3 subunit; potassium channel shaker chain beta 1a; potassium channel, voltage gated subfamily A regulatory beta subunit 1; potassium voltage-gated channel subfamily A member regulatory beta subunit 1; potassium voltage-gated channel, shaker-related subfamily, beta member 1; Potassium voltage-gated channel subfamily A regulatory beta subunit 1

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