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Magic™ Membrane Protein Human KCNH4 (Potassium voltage-gated channel subfamily H member 4) Full Length (CAT#: MPC0597K) Made to Order

Datasheet
This product is a 111.6 kDa Human KCNH4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNH4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 111.6 kDa
  • TMD
  • 6
  • Sequence
  • MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGTRGFPIVYCSDGFC
    ELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLHKALEGHQEHRAEICFY
    RKDGSAFWCLLDMMPIKNEMGEVVLFLFSFKDITQSGSPGLGPQGGRGDS
    NHENSLGRRGATWKFRSARRRSRTVLHRLTGHFGRRGQGGMKANNNVFEP
    KPSVPEYKVASVGGSRCLLLHYSVSKAIWDGLILLATFYVAVTVPYNVCF
    SGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSI
    GLHYLATWFFIDLIAALPFDLLYIFNITVTSLVHLLKTVRLLRLLRLLQK
    LERYSQCSAVVLTLLMSVFALLAHWMACIWYVIGRREMEANDPLLWDIGW
    LHELGKRLEVPYVNGSVGGPSRRSAYIAALYFTLSSLTSVGFGNVCANTD
    AEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIR
    VHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNRE
    ILQLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGS
    LEVLRDNMVLAILGKGDLIGADIPEPGQEPGLGADPNFVLKTSADVKALT
    YCGLQQLSSRGLAEVLRLYPEYGAAFRAGLPRDLTFNLRQGSDTSGLSRF
    SRSPRLSQPRSESLGSSSDKTLPSITEAESGAEPGGGPRPRRPLLLPNLS
    PARPRGSLVSLLGEELPPFSALVSSPSLSPSLSPALAGQGHSASPHGPPR
    CSAAWKPPQLLIPPLGTFGPPDLSPRIVDGIEDSGSTAEAPSFRFSRRPE
    LPRPRSQAPPTGTRPSPELASEAEEVKEKVCRLNQEISRLNQEVSQLSRE
    LRHIMGLLQARLGPPGHPAGSAWTPDPPCPQLRPPCLSPCASRPPPSLQD
    TTLAEVHCPASVGTMETGTALLDLRPSILPPYPSEPDPLGPSPVPEASPP
    TPSLLRHSFQSRSDTFH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNH4
  • Full Name
  • Potassium voltage-gated channel subfamily H member 4
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system.
  • Alternative Names
  • BEC2; ELK1; Kv12.3; potassium voltage-gated channel subfamily H member 4; ELK channel 1; brain-specific eag-like channel 2; ether-a-go-go K(+) channel family member; ether-a-go-go-like potassium channel 1; potassium channel, voltage gated eag related subfamily H, member 4; potassium voltage-gated channel, subfamily H (eag-related), member 4; voltage-gated potassium channel subunit Kv12.3; KCNH4; Potassium voltage-gated channel subfamily H member 4

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