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Magic™ Membrane Protein Human KCNK3 (Potassium two pore domain channel subfamily K member 3) for Antibody Discovery (CAT#: MP1411J)

Datasheet
This product is a 50.5 kDa Human KCNK3 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNK3
  • Protein Length
  • Full-length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 50.5 kDa
  • Sequence
  • MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • N-10xHis and C-Myc
  • Reconstitution
  • Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).
  • Purity
  • >85% as determined by SDS-PAGE
  • Buffer
  • Liquid: Tris/PBS-based buffer, 5%-50% glycerol
    Lyophilized powder: Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • KCNK3
  • Full Name
  • Potassium two pore domain channel subfamily K member 3
  • Introduction
  • This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
  • Alternative Names
  • Acid sensitive potassium channel protein TASK 1; Acid sensitive potassium channel protein TASK; Acid-sensitive potassium channel protein TASK-1; Cardiac two pore background K(+) channel; cTBAK 1; K2p3.1; KCNK3; KCNK3_HUMAN; OAT1; Potassium channel subfamily K member 3; potassium channel, subfamily K, member 3; Potassium inwardly rectifying channel subfamily K member 3; PPH4; rTASK; TASK 1; TASK; TBAK1; TWIK related acid sensitive K+ channel; TWIK-related acid-sensitive K(+) channel 1; Two P domain potassium channel; Two pore K(+) channel KT3.; Two pore K(+) channel KT3.1; Two pore potassium channel KT3.1; OAT1; PPH4; TASK; TASK1; TBAK1; K2p3.1; TASK-1

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