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Magic™ Membrane Protein Human KDSR (3-ketodihydrosphingosine reductase) Full Length (CAT#: MPC4460K) Made to Order

This product is a made-to-order Human KDSR membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KDSR
  • Protein Length
  • Full length
  • Protein Class
  • Oxidoreductase
  • TMD
  • 2
  • Sequence
  • MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAI
    ECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQ
    VENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSV
    YPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL
    QMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQV
    AKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
    RTIALFYLGSFDSIVRRCMMQREKSENADKTA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • KDSR
  • Full Name
  • 3-ketodihydrosphingosine reductase
  • Introduction
  • The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
  • Alternative Names
  • KDSR; DHSR; FVT1; EKVP4; SDR35C1; 3-dehydrosphinganine reductase; FVT-1; KDS reductase; follicular lymphoma variant translocation 1; follicular variant translocation protein 1; short chain dehydrogenase/reductase family 35C member 1; 3-ketodihydrosphingosine reductase

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