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Magic™ Membrane Protein Human MANEA (Mannosidase endo-alpha) Full Length (CAT#: MPC3537K) Made to Order

Datasheet
This product is a made-to-order Human MANEA membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MANEA
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MAKFRRRTCIILALFILFIFSLMMGLKMLRPNTATFGAPFGLDLLPELHQ
    RTIHLGKNFDFQKSDRINSETNTKNLKSVEITMKPSKASELNLDELPPLN
    NYLHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHNPPDDI
    GSSFYPELGSYSSRDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEP
    TDNLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMYKNVKYIIDKYGNHPA
    FYRYKTKTGNALPMFYVYDSYITKPEKWANLLTTSGSRSIRNSPYDGLFI
    ALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWASLKLFCDKYNL
    IFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQTRPSLISIT
    SFNEWHEGTQIEKAVPKRTSNTVYLDYRPHKPGLYLELTRKWSEKYSKER
    ATYALDRQLPVS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • MANEA
  • Full Name
  • Mannosidase endo-alpha
  • Introduction
  • N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
  • Alternative Names
  • MANEA; ENDO; hEndo; glycoprotein endo-alpha-1,2-mannosidase; alpha 1,2-endomannosidase; endo-alpha mannosidase; endomannosidase; mandaselin; Mannosidase endo-alpha

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