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Magic™ Membrane Protein Human NRG1 (Neuregulin 1) Full Length (CAT#: MPC1341K) Made to Order

Datasheet
This product is a 70.3 kDa Human NRG1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NRG1
  • Protein Length
  • Full length
  • Protein Class
  • Growth factor
  • Molecular Weight
  • 70.3 kDa
  • TMD
  • 1
  • Sequence
  • MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAG
    SKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRIN
    KASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSS
    ESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVK
    DLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGIC
    IALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPN
    PPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQT
    PSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRE
    CNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPS
    EMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSS
    FHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRT
    KPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLE
    ATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • NRG1
  • Full Name
  • Neuregulin 1
  • Introduction
  • The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
  • Alternative Names
  • NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; acetylcholine receptor-inducing activity; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; pro-NRG1; sensory and motor neuron derived factor; Neuregulin 1

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