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Magic™ Membrane Protein Human NRG2 (Neuregulin 2) Full Length (CAT#: MPC4068K) Made to Order

Datasheet
This product is a made-to-order Human NRG2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NRG2
  • Protein Length
  • Full length
  • Protein Class
  • Growth factor
  • TMD
  • 1
  • Sequence
  • MRQVCCSALPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSS
    SNNSSISRPAAPPEPRPQQQPQPRSPAARRAAARSRAAAAGGMRRDPAPG
    FSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTR
    EPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCVPLERNQRYIFFLEP
    TEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVG
    EKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNK
    VKVEDAGEYVCEAENILGKDTVRGRLYVNSVSTTLSSWSGHARKCNETAK
    SYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEE
    LYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQ
    NRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCS
    PSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSP
    ACVEARARRAAAYNLEERRRATAPPYHDSVDSLRDSPHSERYVSALTTPA
    RLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRH
    PAPPGPGPGPGPGPGPGADMQRSYDSYYYPAAGPGPRRGTCALGGSLGSL
    PASPFRIPEDDEYETTQECAPPPPPRPRARGASRRTSAGPRRWRRSRLNG
    LAAQRARAARDSLSLSSGSGGGSASASDDDADDADGALAAESTPFLGLRG
    AHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • NRG2
  • Full Name
  • Neuregulin 2
  • Introduction
  • This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.
  • Alternative Names
  • NRG2; DON1; HRG2; NTAK; pro-neuregulin-2, membrane-bound isoform; divergent of neuregulin-1; neural- and thymus-derived activator for ErbB kinases; pro-NRG2; Neuregulin 2

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