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Magic™ Membrane Protein Human RNF170 (Ring finger protein 170) Full Length (CAT#: MPC4544K) Made to Order

This product is a made-to-order Human RNF170 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RNF170
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 3
  • Sequence
  • MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQ
    NIHPENQELVRVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVET
    NCGHLFCGACIIAYWRYGSWLGAISCPICRQTVTLLLTVFGEDDQSQDVL
    RLHQDINDYNRRFSGQPRSIMERIMDLPTLLRHAFREMFSVGGLFWMFRI
    RIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLLLIYISIMYRE
    VITQRLTR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • RNF170
  • Full Name
  • Ring finger protein 170
  • Introduction
  • This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • RNF170; ADSA; SNAX1; E3 ubiquitin-protein ligase RNF170; RING-type E3 ubiquitin transferase RNF170; putative LAG1-interacting protein; Ring finger protein 170

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