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Magic™ Membrane Protein Human SCN4A (Sodium voltage-gated channel alpha subunit 4) Full Length (CAT#: MPC0705K) Made to Order

This product is a 208 kDa Human SCN4A membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCN4A
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 208 kDa
  • TMD
  • 24
  • Sequence
  • MARPSLCTLVPLGPECLRPFTRESLAAIEQRAVEEEARLQRNKQMEIEEP
    ERKPRSDLEAGKNLPMIYGDPPPEVIGIPLEDLDPYYSNKKTFIVLNKGK
    AIFRFSATPALYLLSPFSVVRRGAIKVLIHALFSMFIMITILTNCVFMTM
    SDPPPWSKNVEYTFTGIYTFESLIKILARGFCVDDFTFLRDPWNWLDFSV
    IMMAYLTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKL
    SDVMILTVFCLSVFALVGLQLFMGNLRQKCVRWPPPFNDTNTTWYSNDTW
    YGNDTWYGNEMWYGNDSWYANDTWNSHASWATNDTFDWDAYISDEGNFYF
    LEGSNDALLCGNSSDAGHCPEGYECIKTGRNPNYGYTSYDTFSWAFLALF
    RLMTQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVAMAY
    AEQNEATLAEDKEKEEEFQQMLEKFKKHQEELEKAKAAQALEGGEADGDP
    AHGKDCNGSLDTSQGEKGAPRQSSSGDSGISDAMEELEEAHQKCPPWWYK
    CAHKVLIWNCCAPWLKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHY
    PMTEHFDNVLTVGNLVFTGIFTAEMVLKLIAMDPYEYFQQGWNIFDSIIV
    TLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGAL
    GNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIALDCNLPRWHMHDFFHS
    FLIVFRILCGEWIETMWDCMEVAGQAMCLTVFLMVMVIGNLVVLNLFLAL
    LLSSFSADSLAASDEDGEMNNLQIAIGRIKLGIGFAKAFLLGLLHGKILS
    PKDIMLSLGEADGAGEAGEAGETAPEDEKKEPPEEDLKKDNHILNHMGLA
    DGPPSSLELDHLNFINNPYLTIQVPIASEESDLEMPTEEETDTFSEPEDS
    KKPPQPLYDGNSSVCSTADYKPPEEDPEEQAEENPEGEQPEECFTEACVQ
    RWPCLYVDISQGRGKKWWTLRRACFKIVEHNWFETFIVFMILLSSGALAF
    EDIYIEQRRVIRTILEYADKVFTYIFIMEMLLKWVAYGFKVYFTNAWCWL
    DFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVV
    NALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTTTSERFDI
    SEVNNKSECESLMHTGQVRWLNVKVNYDNVGLGYLSLLQVATFKGWMDIM
    YAAVDSREKEEQPQYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQ
    QKKKLGGKDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDLV
    TKQAFDITIMILICLNMVTMMVETDNQSQLKVDILYNINMIFIIIFTGEC
    VLKMLALRQYYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVI
    RLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFG
    MSNFAYVKKESGIDDMFNFETFGNSIICLFEITTSAGWDGLLNPILNSGP
    PDCDPNLENPGTSVKGDCGNPSIGICFFCSYIIISFLIVVNMYIAIILEN
    FNVATEESSEPLGEDDFEMFYETWEKFDPDATQFIAYSRLSDFVDTLQEP
    LRIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKQT
    MEEKFMAANPSKVSYEPITTTLKRKHEEVCAIKIQRAYRRHLLQRSMKQA
    SYMYRHSHDGSGDDAPEKEGLLANTMSKMYGHENGNSSSPSPEEKGEAGD
    AGPTMGLMPISPSDTAWPPAPPPGQTVRPGVKESLV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SCN4A
  • Full Name
  • Sodium voltage-gated channel alpha subunit 4
  • Introduction
  • Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders.
  • Alternative Names
  • HYPP; SkM1; CMS16; HYKPP; NAC1A; HOKPP2; Nav1.4; Na(V)1.4; sodium channel protein type 4 subunit alpha; CTC-264K15.6; skeletal muscle sodium channel alpha subunit; skeletal muscle voltage-dependent sodium channel type IV alpha subunit; sodium channel protein skeletal muscle subunit alpha; sodium channel protein type IV subunit alpha; sodium channel, voltage-gated, type IV, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.4; SCN4A; Sodium voltage-gated channel alpha subunit 4

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