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Magic™ Membrane Protein Human SLC6A19 (Solute carrier family 6 member 19) Full Length (CAT#: MPC0906K) Made to Order

Datasheet
This product is a 71.1 kDa Human SLC6A19 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC6A19
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 71.1 kDa
  • TMD
  • 12
  • Sequence
  • MVRLVLPNPGLDARIPSLAELETIEQEEASSRPKWDNKAQYMLTCLGFCV
    GLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFAIGQRLRRGS
    LGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPW
    SDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLC
    LACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNG
    IVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCE
    KDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDL
    PEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAF
    IVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIP
    PKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFC
    EMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFF
    VVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGY
    AIYKLIRNHCQKPGDHQGLVSTLSTASMNGDLKY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC6A19
  • Full Name
  • Solute carrier family 6 member 19
  • Introduction
  • This gene encodes a system B(0) transmembrane protein that actively transports most neutral amino acids across the apical membrane of epithelial cells. Mutations in this gene may result in Hartnup disorder, an inherited disease with symptoms such as pellagra, cerebellar ataxia, and psychosis. The expression and function of B0AT1 (SLC6A19) in intestinal cells depends on the presence of the accessory protein angiotensin-converting enzyme 2 (ACE2) which, among other functions, acts as a chaperone for membrane trafficking of B0AT1. The ACE2 is also the cellular receptor for severe acute respiratory syndrome-coronavirus (SARS-CoV) and for SARS-CoV-2 that is causing the coronavirus 2019 (COVID-19) pandemic.
  • Alternative Names
  • HND; B0AT1; sodium-dependent neutral amino acid transporter B(0)AT1; sodium-dependent amino acid transporter system B0; solute carrier family 6 (neurotransmitter transporter), member 19; solute carrier family 6 (neutral amino acid transporter), member 19; system B(0) neutral amino acid transporter AT1; system B0 neutral amino acid transporter; SLC6A19; Solute carrier family 6 member 19

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