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Magic™ Membrane Protein Human ZMPSTE24 (Zinc metallopeptidase STE24) Full Length (CAT#: MPC2530K) Made to Order

This product is a made-to-order Human ZMPSTE24 membrane protein expressed in Saccharomyces cerevisiae. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ZMPSTE24
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • TMD
  • 7
  • Sequence
  • MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTH
    VPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGTLILLFGGIPY
    LWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIE
    EKHGFNQQTLGFFMKDAIKKFVVTQCILLPVSSLLLYIIKIGGDYFFIYA
    WLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLT
    KVYVVEGSKRSSHSNAYFYGFFKNKRIVLFDTLLEEYSVLNKDIQEDSGM
    EPRNEEEGNSEEIKAKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNII
    ISQMNSFLCFFLFAVLIGRKELFAAFGFYDSQPTLIGLLIIFQFIFSPYN
    EVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDW
    LFSMWHYSHPPLLERLQALKTMKQH

Product Description

  • Expression Systems
  • Saccharomyces cerevisiae
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • ZMPSTE24
  • Full Name
  • Zinc metallopeptidase STE24
  • Introduction
  • This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
  • Alternative Names
  • ZMPSTE24; HGPS; PRO1; FACE1; STE24; FACE-1; Ste24p; CAAX prenyl protease 1 homolog; farnesylated proteins-converting enzyme 1; prenyl protein-specific endoprotease 1; zinc metallopeptidase STE24 homolog; zinc metalloproteinase Ste24 homolog; Zinc metallopeptidase STE24

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