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Magic™ Membrane Protein Human MERTK (MER proto-oncogene, tyrosine kinase) Expressed in Baculovirus/Insect expression system for Antibody Discovery, Partial (26-499aa) (CAT#: MPX0275K)

Datasheet
This product is a 78 kDa Human MERTK membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MERTK
  • Protein Length
  • Partial (26-499aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 78 kDa
  • TMD
  • 1
  • Sequence
  • REEAKPYPLFPGPFPGSLQTDHTPL
    LSLPHASGYQPALMFSPTQPGRPHTGNVAIPQVTSVESKPLPPLAFKHTV
    GHIILSEHKGVKFNCSISVPNIYQDTTISWWKDGKELLGAHHAITQFYPD
    DEVTAIIASFSITSVQRSDNGSYICKMKINNEEIVSDPIYIEVQGLPHFT
    KQPESMNVTRNTAFNLTCQAVGPPEPVNIFWVQNSSRVNEQPEKSPSVLT
    VPGLTEMAVFSCEAHNDKGLTVSKGVQINIKAIPSPPTEVSIRNSTAHSI
    LISWVPGFDGYSPFRNCSIQVKEADPLSNGSVMIFNTSALPHLYQIKQLQ
    ALANYSIGVSCMNEIGWSAVSPWILASTTEGAPSVAPLNVTVFLNESSDN
    VDIRWMKPPTKQQDGELVGYRISHVWQSAGISKELLEEVGQNGSRARISV
    QVHNATCTVRIAAVTRGGVGPFSDPVKIFIPAHGWVDYAPSSTPAPGNA

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • MERTK
  • Full Name
  • MER proto-oncogene, tyrosine kinase
  • Introduction
  • This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
  • Alternative Names
  • MERTK; MER; RP38; c-Eyk; c-mer; Tyro12; tyrosine-protein kinase Mer; MER receptor tyrosine kinase; STK kinase; c-mer proto-oncogene tyrosine kinase; proto-oncogene c-Mer; receptor tyrosine kinase MerTK; MER proto-oncogene, tyrosine kinase

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