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NativeExtract™ Human ADGRE2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX404)

Datasheet
This product is recombinant Human ADGRE2 protein in native nanodisc form. The synthetic compound we developed can solubilize the ADGRE2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRE2
  • Protein Length
  • Full length
  • Molecular Weight
  • 90.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADGRE2
  • Full Name
  • Adhesion G protein-coupled receptor E2
  • Introduction
  • This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • VBU; CD97; EMR2; CD312; CD97 antigen; EGF-like module-containing mucin-like hormone receptor-like 2; Leukocyte antigen CD97; egf-like module containing, mucin-like, hormone receptor-like 2; ADGRE2; Adhesion G protein-coupled receptor E2

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