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NativeExtract™ Human CRHR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX285)

Datasheet
This product is recombinant Human CRHR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CRHR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CRHR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 36.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CRHR1
  • Full Name
  • Corticotropin releasing hormone receptor 1
  • Introduction
  • This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.
  • Alternative Names
  • Corticotropin releasing hormone (CRH)

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