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NativeExtract™ Human LHCGR Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX173)

Datasheet
This product is recombinant Human LHCGR protein in native nanodisc form. The synthetic compound we developed can solubilize the LHCGR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LHCGR
  • Protein Length
  • Full length
  • Molecular Weight
  • 78.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • LHCGR
  • Full Name
  • Luteinizing hormone/choriogonadotropin receptor
  • Introduction
  • This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.
  • Alternative Names
  • HHG; LHR; LCGR; LGR2; ULG5; LHRHR; LSH-R; LH/CGR; LH/CG-R; lutropin-choriogonadotropic hormone receptor; hypergonadotropic hypogonadism; lutropin/choriogonadotropin receptor; LHCGR; Luteinizing hormone/choriogonadotropin receptor

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