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NativeExtract™ Human PROKR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX392)

Datasheet
This product is recombinant Human PROKR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the PROKR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PROKR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 44.8 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PROKR1
  • Full Name
  • Prokineticin receptor 1
  • Introduction
  • This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage.
  • Alternative Names
  • ZAQ; PKR1; GPR73; PK-R1; GPR73a; G protein-coupled receptor 73; G protein-coupled receptor ZAQ; PROKR1; Prokineticin receptor 1

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