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Human SS-A Autoantibody (IgG) ELISA kit (CAT#: NAK-061)
This product is an ELISA kit for the determination of SS-A Autoantibody in human Plasma or Serum. It is highly sensitive and available for the detection of SS-A Autoantibody as low as 1.0 U/mL (12.5 to 200 U/mL).
| Specifications | |
|---|---|
| Sensitivity | 1.0 U/mL (12.5 to 200 U/mL) |
| Assay Type | ELISA |
| Pack size | 1×96 wells |
| Species Reactivity | Human |
| Antibody Type | IgG |
| Contents | Divisible microplate Calibrators (A-F) Control positive IgG (1) Control positive IgA (2) Sample buffer P (5x) Enzyme Conjugate TMB substrate Stop solution Wash solution (50x) |
| Sample Requirement | Plasma, Serum: 10ul |
| Storage | Short term: 4°C, Long term: See manual. |
| Target Information | |
|---|---|
| Target | SS-A autoantibody |
| Introduction | SSA or Ro is composed of protein antigens of 52 kD and 60 kD combined with cytoplasmic RNA species. SSA antibodies occur in patients with several different connective tissue diseases including Sjogren syndrome, an autoimmune disease that involves primarily the salivary and lachrymal glands (up to 90% of cases); systemic lupus erythematosus (SLE) (40%-60% of cases); and rheumatoid arthritis. SSA antibodies are associated with childhood SLE, neonatal SLE, and with congenital heart block in infants born to mothers with SLE. SSA antibodies have also been reported to be associated with features of extraglandular inflammation in patients with SLE including vasculitis, purpura, cytopenias, and adenopathy. |
DatasheetFor Research Use Only | Not For Clinical Use
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