Human Zinc transporter 8 (SLC30A8) Autoantibody (IgG) ELISA kit (CAT#: NAK-011)

This product is a qualitative kit for the determination of Zinc transporter 8 (SLC30A8) Autoantibody in human Plasma or Serum.

Specifications
Sensitivity	Qualitative
Assay Type	ELISA
Pack size	1×96 wells
Species Reactivity	Human
Antibody Type	IgG
Contents	Coated assay plate 1(96 wells) Negative Control Positive Control Sample Diluent HRP-conjugate Wash Buffer Substrate A Substrate B Stop Solution
Sample Requirement	Plasma, Serum: 50-100ul
Storage	Short term: 4°C, Long term: See manual.

Target Information
Target	Zinc transporter 8 (SLC30A8) autoantibody
Alternative Names	Solute Carrier Family 30 Member 8 autoantibody; ZnT-8 2 autoantibody; ZNT8 2 autoantibody; Zinc Transporter 8 autoantibody; Solute Carrier Family 30 (Zinc Transporter), Member 8 autoantibody; Zinc Transporter ZnT-8 autoantibody
Introduction	The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.

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