The solute carrier family 17 (SLC17) is part of the larger group of transporters found in prokaryotes and eukaryotes that make up the Anion: Cation Symporter Family within the Major Facilitator Superfamily. It is composed of nine genes that have previously been functionally divided into four subgroups. The first characterized members of this family are the type I phosphate transporters (SLC17A1–4) that were initially identified as Na+-dependent inorganic phosphate (Pi) transporters. Other identified mammalian members of this family include a lysosomal acidic sugar transporter (SLC17A5), vesicular glutamate transporters (SLC17A7, SLC17A6, and SLC17A8 respectively), and a vesicular nucleotide transporter (SLC17A9). Studies have shown that members of the SLC17 family are involved in the transporting of amino acids: glutamate, aspartate as well as nucleotides.
Here, we have described in detail of members of the solute carrier family 17, which includes but not limited to SLC17A1, SLC17A3, and SLC17A5. To learn more detailed information, please click the links below.
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