Formulation Analysis and Characterization Services
Analysis and Characterization Our Features Workflow Case Study
The study and characterization of lipid-based delivery systems are essential for drug design, mechanistic studies, formulation development, along with quality control. This can be achieved through analyzing parameters such as lamellar arrangement, composition, morphology, size, polydispersity, Zeta potential, drug release, among others.
Analysis and Characterization in Creative Biolabs
To facilitate the development and application of lipid-based delivery systems, Creative Biolabs offers comprehensive analysis and characterization services.
Our Featured Service
Morphology
The morphological analysis of liposomes helps to understand their size, shape, surface modification, homogeneity and degree of aggregation, and other important information.
Creative Biolabs offers SEM, TEM, cryogenic TEM (cryo-TEM) testing services, you will get 1-3 images per sample.
Particle size and polymer dispersity index (PDI)
Liposomes' size is an important aspect in influencing their properties and safety in biological systems.
Creative Biolabs provides dynamic light scattering (DLS) testing service, you will get 3 sets of particle size report for each sample.
Zeta potential
Zeta potential measurements provide for the accurate analysis of the liposome surface's electrical state, allowing for the prediction of its stability.
Creative Biolabs provides 1-3 sets of Zeta potential curves for each sample.
Encapsulation Efficiency (EE) and Drug Loading (DL)
Increasing the EE and DL will help to the improvement of drugs bioavailability.
Creative Biolabs utilizes HPLC/UV for drug quantification, which is used for the calculation of EE and DL.
In Vitro Release (IVR)
IVR testing imitates the drug release process of liposomes in vivo, making it an essential tool for assessing liposome quality and the in vitro in vivo correlation (IVIVC). It can be carried out with the appropriate release media at 37 °C under sink conditions.
Creative Biolabs can tailor the most suitable release conditions for your project, including temperature, speed, and release media, based on your needs.
Others
Please contact us for more detailed information on additional characterization parameters, such as lamellarity, stability, safety, etc.
Workflow
Creative Biolabs offers a comprehensive formulation analysis and characterization service with a focus on providing accuracy and efficiency. Our service is designed to provide clients with comprehensive insights into the properties and composition of nanoparticles such as liposomes.
Sample Reception: Clients provide us with their liposome samples for analysis.
Sample Preparation: Our experienced team ensures proper handling and preparation of the samples to maintain their integrity.
Detection: Our advanced technology platform enables diverse analysis and characterization of liposomes.
Delivery of Analysis Report: Upon completion of the analysis, clients receive a detailed report outlining the findings and recommendations.
Case Study
Explore our success stories through a detailed case study on our liposome product.
Fig.1 TEM image of liposomes.
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Particle size and polymer dispersity index (PDI)
Fig.2 Average particle size and PDI of liposomes.
Fig.3 Zeta potential of liposomes.
Creative Biolabs has always been at the forefront of global exploration in lipid-based delivery systems while maintaining a commitment to quality, accuracy, and customer satisfaction. Our cutting-edge technology and expertise in formulation analysis and characterization make us the ideal partner for your liposome research needs. Contact us today to learn more about how we can assist you in achieving your research goals.
For Research Use Only. Not For Clinical Use
