Get Expert Solutions for Your Lipid-based Delivery Research!

Creative Biolabs offers comprehensive solutions in lipid-based delivery. With expertise spanning over a decade and a commitment to excellence, we are the trusted partner for global clients. From development to analysis, our innovative services empower researchers to achieve breakthroughs in drug delivery research.

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Services Platforms Applications Process Advantages FAQs Resources

Why Lipid-based Delivery Systems?

Lipid-based delivery systems have emerged as powerful tools in pharmaceutical research due to their ability to address the solubility and bioavailability challenges of poorly water-soluble drugs. Their versatility enables the encapsulation of both hydrophilic and hydrophobic molecules, while their superior biocompatibility ensures safe and controlled drug delivery.

Lipid-based delivery systems are utilized across various administration routes, including oral, ocular, intranasal, dermal, transdermal, parenteral, and vaginal. These systems can efficiently integrate with the lipid matrix of the skin, enhancing permeability and making them ideal for transdermal drug delivery. In addition, they safeguard encapsulated molecules from enzymatic or chemical degradation, allowing controlled release and improved therapeutic outcomes. With surface modifications, such as PEGylation or antibody conjugation, lipid-based systems can achieve targeted delivery, making them highly functionalized drug carriers.

Fig.2 Different drugs for liposomal delivery (Creative Biolabs Original)

Key Services

Lipid-based Delivery System Development

Creative Biolabs develops a wide range of lipid-based carriers, including liposomes, LNPs, SLNs, etc. These are consistency, scalability, and high encapsulation efficiency. We also offer functionalized delivery system development services, such as PEGylated liposomes for prolonged circulation and immunoliposomes for specific targeting, customized for diverse applications.

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Formulation Analysis and Characterization

We offer services including structure analysis (lamellarity, phase behavior), basic characterization (morphology, size, PDI, zeta potential, EE), in vitro release kinetics analysis, and stability and safety evaluations to ensure optimal performance, stability, and quality of lipid-based delivery systems.

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Pharmacodynamic Study Services

We use in vitro and in vivo models to evaluate lipid-based drug efficacy. Our services include PK-PD analysis and multi-omics analysis to explore pharmacological activities, nanoparticle distribution, and molecular mechanisms, ensuring precise data interpretation and optimized drug delivery strategies.

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Fig.5 Lipid-based delivery services technology-3 (Creative Biolabs Authorized)
Fig.3 Lipid-based delivery services technology-1 (Creative Biolabs Authorized)
Fig.4 Lipid-based delivery services technology-2 (Creative Biolabs Authorized)
Fig.5 Lipid-based delivery services technology-3 (Creative Biolabs Authorized)
Fig.3 Lipid-based delivery services technology-1 (Creative Biolabs Authorized)

Advanced Platforms and Technology Support

Creative Biolabs offers several advanced platforms and technologies to support lipid-based drug delivery research. Alongside our flagship LipoDrive™ Platform, other available platforms include:
Microfluidics Technology: Ensures precise control over liposome and nanoparticle formation, achieving uniform particle sizes and encapsulation efficiency.

  • Cryo-TEM Analysis: Provides high-resolution imaging of liposome lamellarity and internal structure.
  • SAXS and NMR Platforms: Used for characterizing lipid bilayers and phase transitions.
  • ³¹P NMR: Analyzes the phosphorus content and lipid composition.
  • High-throughput Screening Systems: Identifies optimal lipid formulations rapidly, improving efficiency and reducing development time.
Fig.6 Lipid-based delivery services partner-1 (Creative Biolabs Authorized)
Fig.7 Lipid-based delivery services partner-2 (Creative Biolabs Authorized)
Fig.8 Lipid-based delivery services partner-3 (Creative Biolabs Authorized)
Fig.9 Lipid-based delivery services partner-4 (Creative Biolabs Authorized)
Fig.10 Lipid-based delivery services partner-5 (Creative Biolabs Authorized)
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Join industry leaders in leveraging our top-tier lipid-based delivery solutions—contact us today for inquiries and custom service quotes.

Applications of Lipid-based Systems

Application Area Description
Therapeutics Effective for treating infectious, inflammatory, and neuropathic diseases, as well as cancer and gene delivery applications.
Immune Activation Used in vaccine formulations to enhance immune responses.
Diagnostics and Imaging Employed in medical imaging and diagnostic tools to improve accuracy and targeting.
Food and Nutraceuticals Incorporated into food products for nutrient delivery and bioavailability enhancement.
Cosmetics Utilized in skincare formulations for deep penetration and controlled release of active ingredients.
Agriculture Supports crop protection and nutrient delivery to plants.
Artificial Cells Enables the development of synthetic cells for research purposes.
Veterinary Medicine Delivers therapeutic agents in animal healthcare.
Textile Industry Integrated into fabrics for functional textile applications, such as antimicrobial finishing.

Click the Video to Learn More about Liposomal Delivery Systems in Cancer Therapy

Fig.11 Lipid-based delivery services partner-5 (Creative Biolabs Authorized)

Service Process for Lipid-based Delivery at Creative Biolabs

Step 1: Contact & Requirements

Clients begin by contacting Creative Biolabs to discuss their specific project needs and goals. A thorough understanding of the requirements is established to align the project direction with the client’s expectations.

Fig.12 Contact & requirements (Creative Biolabs Original)
Fig.13 Technical support & custom plan (Creative Biolabs Original)

Step 2: One-to-one Technical Support & Custom Plan

Our experienced technical team provides personalized consultation to recommend the most suitable approach for the project. After assessing the client's needs, a detailed custom plan is formulated, covering all aspects of lipid-based carrier development.

Step 3: Submission of Custom Service Form

The client submits a service form to confirm the agreed specifications. This document outlines key project parameters, ensuring both sides have a clear understanding of the workflow and milestones.

Fig.14 Submission of custom service form (Creative Biolabs Original)
Fig.15 Project start & sample reception (Creative Biolabs Original)

Step 4: Project Start & Sample Reception

Once the project is initiated, Creative Biolabs begins by developing the liposome formulation according to the agreed plan. If the project requires testing or analysis, the client sends samples for reception and preparation by our experts to maintain integrity and consistency.

Step 5: Liposome Preparation

During this stage, the liposomal structure is formulated using lipid film formation followed by hydration with the drug solution. Surface modifications, such as PEGylation or antibody conjugation, are applied based on the client’s objectives. This stage ensures that the formulation achieves the desired stability, encapsulation efficiency, and functionality.

Fig. 16 Liposome preparation (Creative Biolabs Original)
Fig. 17 Detection & optional pharmacodynamic studies (Creative Biolabs Original)

Step 6: Detection & Optional Pharmacodynamic Studies

Comprehensive analysis and characterization are conducted to ensure product quality. The testing includes measurements of particle size, zeta potential, drug release profiles, and encapsulation efficiency (EE). Additionally, in vitro and in vivo pharmacodynamic studies may be performed to assess the biological activity of the formulation.

Step 7: Final Report and Product Delivery

A detailed analysis report and the finalized product are securely packaged and delivered to the client. We ensure timely delivery and provide ongoing support for any post-delivery inquiries.

Fig. 18 Final report and product delivery (Creative Biolabs Original)

Advantages of Our Lipid-based Delivery Services

Creative Biolabs offers exceptional lipid-based drug delivery services, leveraging decades of expertise and advanced technology platforms. With a full-service approach, we support every step of the research process, from custom lipid synthesis to pharmacodynamic studies, ensuring precise and reliable results. Our solutions are tailored to meet the specific needs of each project, empowering researchers worldwide to achieve breakthroughs with confidence.

  • Global Expertise
  • Comprehensive Solutions
  • Advanced Technology
  • Diverse Model Library
  • Personalized Support
  • High Scalability
  • Cost-effectiveness

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Advantages of Our Lipid-based Delivery Services

FAQs

Do you provide preformed liposomes?
Yes, we offer preformed liposomes, such as fluorescent, PEGylated, and clodronate liposomes for research purposes.
Can lipid-based systems support both hydrophilic and hydrophobic drugs?
Yes, lipid-based carriers can encapsulate both hydrophilic and hydrophobic molecules, ensuring enhanced stability and delivery.
How does Creative Biolabs ensure scalability and consistency?
Our LipoDrive™ Platform and advanced production techniques ensure high encapsulation efficiency, batch uniformity, and scalability.
Can you assist with targeted drug delivery?
Yes, we develop functionalized liposomes, including immunoliposomes and PEGylated liposomes, for targeted delivery applications.
How long does the service process take?
Timelines vary based on project complexity, but we ensure rapid turnaround and continuous technical support throughout the process.

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