Glutaryl-Liposome (CAT#: CLBD022LY)

Description
Glutaryl-Liposome is Liposome with the carboxyl group, which can be activated by EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide) and react with sulfo-NHS (N-hydroxysulfosuccinimide) to produce a significantly more stable and more soluble active intermediate (NHS ester). The intermediate can covalently conjugate to the amine group on the proteins, peptides or antibodies through displacement of sulfo-NHS group by amine.
Lipid Composition
L-alpha-Phosphatidylcholine, Cholesterol, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(glutaryl)
Buffer
PBS
pH
6
Storage
Store in dark at +4°C and do not freeze
Size
100 nm
Quantity
5mL (available in lyophilized powder)
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DataSheet MSDS
FAQs Customer Reviews Related Sections
  1. What is Glutaryl-Liposome?

    Glutaryl-Liposome is a liposome with a carboxyl group that can be activated for covalent conjugation with proteins, peptides, or antibodies using EDC and sulfo-NHS.

  2. What pH range is most efficient for EDC activation reactions?

    EDC activation reactions are most efficient at pH 4.7-6.0.

  3. How do Glutaryl-Liposomes compare to non-functionalized liposomes?

    Glutaryl-Liposomes offer more specific conjugation capabilities and enhanced stability due to covalent linking.

  4. Why is pH 6 chosen for the PBS buffer in this product?

    pH 6 is chosen to optimize the efficiency of the EDC activation reactions.

  • Enhanced Targeting Capability
    Using Glutaryl-Liposomes has significantly improved the targeting capability of our conjugated proteins in drug delivery studies.
  • High Specificity
    The high specificity of Glutaryl-Liposome conjugation has significantly improved the accuracy of our targeted therapies.
  • Essential Research Tool
    Glutaryl-Liposome has become an essential tool in our research, providing stable and specific conjugation capabilities.
  • Improved Research Quality
    Glutaryl-Liposomes from Creative Biolabs have enhanced the quality and precision of our research experiments.

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For Research Use Only. Not For Clinical Use

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