Topotecan Hydrochloride (TPT) is a semi-synthetic derivative of the plant alkaloid camptothecin (CPT) with cytotoxic properties. Like other drugs in the CPT family, TPT is a specific inhibitor of topoisomerase I, causing lethal DNA damage in the S phase of mitosis. Liposome preparation and anti-tumor activity research. This product is a pre-formulated liposome encapsulating Topotecan Hydrochloride. It is only for research purposes.
Lipid Composition
HSPC, Cholesterol, DSPE‑mPEG (2000)
Encapsulated Drug
Topotecan Hydrochloride
Buffer
Ammonium Sulfate, pH 4.5
Storage
Store in dark at +4°C and do not freeze
Size
100-200 nm
Quantity
5mL (available in lyophilized powder)
Dosage
Download
DataSheet
MSDS
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