Topotecan Hydrochloride (TPT) is a semi-synthetic derivative of the plant alkaloid camptothecin (CPT) with cytotoxic properties. Like other drugs in the CPT family, TPT is a specific inhibitor of topoisomerase I, causing lethal DNA damage in the S phase of mitosis. Liposome preparation and anti-tumor activity research. This product is a pre-formulated liposome encapsulating Topotecan Hydrochloride. It is only for research purposes.