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Magic™ Antibody Discovery - Human DcR3 / TNFRSF6B (30-300) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1358F)

Datasheet
This membrane protein is Human DcR3 / TNFRSF6B (30-300). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DcR3 / TNFRSF6B
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 56.2 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Val 30 - His 300 (Accession # O95407-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • DcR3 / TNFRSF6B
  • Full Name
  • TNF receptor superfamily member 6b
  • Introduction
  • This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.
  • Alternative Names
  • M68; TR6; DCR3; M68E; DJ583P15.1.1; tumor necrosis factor receptor superfamily member 6B; decoy receptor 3 variant 1; decoy receptor 3 variant 2; decoy receptor for Fas ligand; tumor necrosis factor receptor superfamily, member 6b, decoy

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